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Wednesday, September 16, 2020

Simplicef For Dog Allergies | Cefpodoxime For Allergies

Can I use Simplicef (Cefpodoxime proxetil) for dogs allergic reactions?. This is a very important question to answer. So, in the following article, I decided to discuss How veterinary antibiotic drug helps to treat dog allergies?.

 

Antibiotic (anti means "against" and biotic means "bacteria") are the chemical substances that are used to treat infectious diseases caused by bacteria (single: bacterium). Bacteria are very small, microscopic living organisms that cause bacterial infections.


simplicef-for-dog-allergies


The unnecessary use of antibiotic drugs may cause antibiotic resistance in the body that may be harmful. So, always consult a veterinarian, doctor, pharmacist, or physician before taking an antibacterial drug. Although, all antibiotics including Simplicef 100mg and 200mg tablets (by Zoetis pharmaceuticals) are prescription drugs and need a valid prescription to buy.


An allergic reaction is an automatic response against a foreigner substance by the body's immune system.


Now I am going back to our primary topic that is Simplicef medication for dog allergies.

 

How Does Simplicef Tablets Treat Allergies In Dogs?


The answer is a little complicated because antibiotics do not treat allergies or allergic reactions directly but are used to treat the secondary bacterial infections caused by a primary allergic reaction.


Simplicef is the best FDA (Food and Drug Administration) approved third-generation cephalosporin (cephalosporin is the class of antibiotic drugs) for animals. It effectively kills bacteria by disrupting the bacterial cell wall. It prohibits the process of bacterial cell wall synthesis. 


A veterinarian may suggest Cefpodoxime proxetil, the active ingredient in Simplicef tablets, for the treatment of secondary bacterial infection in a dog. The treatment should not exceed the 30 days period. Usually, a dog may experience progress within the first 3 days of using this medication.   


But if you're not experiencing progress by using cefpodoxime antibiotic medication within 3 days, it's advised to re-visit your dog's veterinarian and consult about the condition.


The recommended dose for cefpodoxime proxetil in dogs is from (minimum) 2.3mg/lb to (maximum) 4.5mg/lb. A veterinarian may suggest the ideal dosage plan for your pet after diagnosing the bacterial infection or the severity of the infection. 


Types of Allergies in Dogs

There are three major types of allergic reactions in dogs.

  • Food allergy
  • Environmental allergy
  • Insect allergy
All these types of dog allergies cause different types of symptoms like,

  • redness of skin
  • swelling or inflammation of different parts of the body (including eyelids, jaw, paws, face, etc)
  • sneezing
  • coughing
  • moderate to severe itching
  • hives
  • licking on the skin (including licking the paws, genital area, and other parts of the body)
  • runny nose
  • waterly and red eyes
  • vomiting
  • diarrhea
  • Upset stomach/gastrointestinal problems like gas, bloating, etc (due to food allergy)
  • difficulty in breathe

Food Allergy


A broad range of dog food brands is available in the market. But some of them may not be suitable for your pet because they may cause food allergy. Here, I am not discussing the taste or foods that your pet likes or does not. I am trying to say that there are certain types of foods that a dog may like to eat but its body responds differently.

food-allergies-in-dogs


The reasons for food allergies may be different. A dog whose body is hypersensitive to any of the food ingredients may cause allergic reactions in the body.  

Symptoms


Food allergy in a dog may cause the following adverse reactions in the body.

  • Diarrhea
  • Abdominal pain
  • Upset stomach
  • Gas
  • Bloating
  • GERD (Gastroesophageal Reflux Disease)
  • Gastrointestinal bacterial infection
  • Fever
  • Loss of appetite (anorexia disease)
  • Swelling and inflammation of the face and other parts of the body (in rare cases)

Treatment


Simply stop providing that kind of food that causes allergies in your dog. If you're not aware of that food, the food allergic test would be formed for your pet by the veterinarian.

Simplicef (cefpodoxime proxetil) 100mg film-coated tablets may be used to treat bacterial infections in dogs including persistent diarrhea and other gastrointestinal (soft tissue) infections.

Antibiotics are used to treat secondary bacterial infections caused by food allergies in dogs.

Environmental Allergy

In this case, a foreigner substance like dust particles, pollen, mold, polluted air may cause allergies in dogs. Usually, it happens due to environmental changes and it may also define as the seasonal allergic reactions in pets.

environmental-allergies-in-dogs


However, changes in the environment may not be in your dog's favor. Because it may cause environmental allergies in dogs.

Symptoms


A dog with environmental allergy may face the following adverse reactions;

  • Sneezing
  • Coughing
  • Runny nose
  • Itching
  • Redness of skin
  • Swelling and inflammation of eyelids, face, paws, genitals, or other parts of the body
  • Difficulty in breathe
  • Hives
  • Skin rashes
In this case, the chances of developing a secondary bacterial infection are very high. It's because when a dog bites or scratches the body due to itching, rashes, rashes, etc, the bacteria may grow and develop a bacterial infection.

Treatment


Anti-itching sprays and other topical lotions, creams, and powders are available in the market that provides instant relief. However, a veterinarian visit is essential if the dog's situation is critical. 

A veterinarian may also suggest anti-allergy or anti-histamine medication. Antibiotics drugs (Simplicef) are used to treat secondary bacterial infections caused by scratching or persistent itching.

Insects Allergy

Flea's and other insects present in a dog's body may cause allergic reactions. It's because flea's saliva causes itching. 
insect-allergies-in-dogs


Symptoms


The symptoms of insect allergies in dogs are the same as others.

  • Skin rashes
  • Swelling and redness on the skin
  • Constant itching
  • Scabies
  • Hives
The chances of secondary bacterial infections are always high in the case of insect allergies. Simplicef (cefpodoxime proxetil) is a third-generation cephalosporin drug used to treat a broad range of bacterial infections caused by both gram-positive and gram-negative types of bacteria.

Treatment


A veterinarian may suggest anti-allergic oral medication for your dog or may prescribe anti-itching sprays/lotions/creams to minimize symptoms. If a secondary bacterial infection has developed, then a veterinarian may suggest antibiotic treatment. Simplicef or Cefpodoxime proxetil antibiotic medication is advised to use for at least 3-7 days or by the recommendation of a veterinarian. 

The recommended dose of Cefpodoxime proxetil tablets varies from a minimum dose of 2.3mg/lb to a maximum of 4.5mg/lb for dogs.

At last, Antibiotic drugs do not treat allergies in dogs but they are used to treat secondary bacterial infections that may develop through scratching, biting, or licking the body parts. Simplicef is a broad-spectrum antibacterial medicine that can be used to treat a variety of infectious diseases caused by bacteria (single: bacterium).

Tuesday, August 11, 2020

Can You Crush Simplicef For Dogs? - Antibiotics For Dogs

Simplicef tablets are used to treat a broad range of bacterial infections caused by bacteria in canine, feline, and other animal species. This is an FDA (Food and drug administration) approved antibiotic drug which is used against a variety of gram-positive and gram-negative bacteria. It kills bacteria by stopping the process of bacterial cell wall synthesis. 

It contains an active ingredient "Cefpodoxime proxetil", a third-generation cephalosporin (a class of antibiotic drugs). Cephalosporins like cefixime, cefprozil, cefuroxime, cefepime, etc are some famous examples of broad-spectrum antibiotics. 

Simplicef, the trademark of Zoetis pharmaceutical, comes in film-coated (sugar-coated) tablets form. It's recommended dosage for canine is between 2.3mg per pound to 4.5mg per pound or 5mg per kg to 10mg per one kilogram.


can-you-crush-simplicef-for-dogs


It's not available in liquid suspension form. Simplicef sugar-coated (polymer-based coat) tablets are available in 100mg and 200mg strengths.  Therefore, sometimes it becomes hard to give the exact prescribed dose without cutting or crushing the simplicef (cefpodoxime proxetil) film-coated tablets

Can Simplicef Be Crushed?


Yes. Simplicef film-coated or sugar-coated tablets can be crushed. Sometimes it becomes necessary to crush or cut a tablet to provide the ideal dose for a patient. A film-coated tablet can be crushed but after crushing its taste would be unpleasant or bitter.

A film-coat is a thin 20-100micro-meter layer. The layer provides a barrier between the medicine (which can be bitter in taste) and the body. It helps to avoid the unpleasant taste of medicine.

However, you should never crush or cut a modified release, extended-release, enteric-coated tablet. Because the purpose of this coating is different. For example, a modified or extended-release tablet is designed to release slowly in the stomach. If you crush or cut a modified release or extended-release tablet, then the purpose will destroy.

An enteric-coated tablet is designed to protect the tablet from stomach acid which can decrease its absorption and efficacy.

Simplicef tablets are film-coated. They can be crushed. But after crushing, it provides an unpleasant and bitter taste. But there is no effect on the efficacy, absorption, and the stability of the drug.

Why Are Simplicef Film-Coated Tablets Crushed?


Simplicef contains "Cefpodoxime proxetil", an antibiotic formulation to treat infectious diseases in dogs, cats, and other small animals. It's a highly recommended medicine by the veterinarians for all soft tissue infections like urinary tract infections, bladder, infection, kidneys infection, nose bacterial infection, ear infection, eye infection, all types of skin infections (including folliculitis, cellulitis, pyoderma), gums infection and other not described here. 

These film-coated are provided in 100mg and 200mg powers. A suggested dose for a pet is 2.3 to 4.5 milligrams per one pound. Sometimes it becomes essential to cut and crush them, so you can provide the ideal dose.

Simplicef Dosage Chart For Dogs

Below is the complete Simplicef dosage chart for dogs by weight. 

 Weight in Pounds (LB) Dose in Milligrams (MG)
05 11.5 To 22.5 mg per day (24 hours)
10  23 To 45 mg per day (24 hours)
15 34.5 To 67.5 mg per day (24 hours)
20 46 To 90 mg per day (24 hours)
25 57.5 To 112.5 mg per day
30 69 To 135 mg per day
35 80.5 To 157.5 mg per day
40 92 To 180 mg per day 
45

103.5 To 202.5 mg per day


You can also find the ideal dosage for your pet by commenting on this article. If you have more queries or questions related to the topic. Then feel free to ask me.

Sunday, August 9, 2020

Does Simplicef (Cefpodoxime) Need To Be Given With Food?

This article explains that whether "Is it necessary to give Simplicef (Cefpodoxime proxetil) tablets with food or not?" It's a veterinary antibiotic drug that is used to treat a broad range of bacterial infections in dogs, cats, and almost all small animals. 


Simplicef Tablets are available in two strengths, 100mg and 200mg respectively. They contain an active ingredient "Cefpodoxime proxetil" which is a broad-spectrum, third-generation cephalosporin, that treats all types of bacterial diseases caused by gram-positive and gram-positive bacteria. 

simplicef-for-dogs-with-or-without-food

Cefpodoxime works against bacteria that contain a cell wall. Because they kill bacteria by disrupting the bacterial cell wall. Cephalosporins including cefixime, cefuroxime, cefepime, cefprozil, etc are not effective against bacteria who lack a cell wall, e.g, Cytoplasmic bacteria.


Cefpodoxime Proxetil With OR Without Food


So, get back to our primary question, "should simplicef for dogs be given with food or not?". Simplicef (cefpodoxime proxetil) for dogs may be given with or without food. It's not necessary to give cefpodoxime with food. However, in some dogs, Simplicef antibiotic tablets may cause stomach upset when given on an empty stomach.


So, to avoid an upset stomach, it's recommended to give simplicef antibiotic medication to canine and feline with food. There is not a huge difference in the absorption of cefpodoxime proxetil (in a dog body) when it's given with food or an empty stomach.

Adverse Reactions Of Taking Simplicef On An Empty Stomach

However, it is not necessary that cefpodoxime proxetil will show side effects and adverse reactions when given on an empty stomach. Antibiotics are hard on the stomach. So, it's advised that take this medication for your dog on a full stomach to avoid abdominal problems. 

A dog may get the following unwanted consequences when taking an antibiotic drug on an empty stomach.

  • Abdominal Cramps
  • Upset Stomach
  • Lethargy 
  • Vomiting
  • Diarrhea
  • Nausea
  • Abdominal Pain
  • GERD (gastroesophageal reflux disease)
  • Gas 
  • Bloating

Simplicef Efficacy With and Without Food

A dog may take cefpodoxime with or without food because it does not make a huge difference in the absorption of this drug in the body. 

The recommended dose of cefpodoxime proxetil for dogs is between 2.3mg per one pound to 4.5mg per one pound. A vet may suggest the ideal dose plan after diagnosing the type of infection. This is a prescription drug and is not available without a vet prescription. 

If anyone of you has any further related queries then feel free to ask me. You can comment below this article or mail me. 

Saturday, August 8, 2020

Is Simplicef Safe For Humans? Dog Antibiotic For Humans

If you're confused about some questions like "Can Humans take Simplicef for dogs?" or "Is simplicef a human drug?". Then, you're at the right place, because today in the following short but a brief piece of article, I have answered these questions. I will also clarify that "Why should humans not take veterinary drugs?" and the possible side effects or adverse reactions that may occur.

is-simplicef-safe-for-humans

Basically, Simplicef is an FDA approved, antibacterial drug, which contains "Cefpodoxime proxetil" composition that kills bacteria by disrupting the bacterial cell wall. It's a third-generation cephalosporin drug, a strong antibiotic for dogs, cats, and other small animals. 


Orelox tablets/liquid by Sanofi Aventis pharmaceutical contains the same ingredient "Cefpodoxime proxetil" and uses to treat bacterial infections in humans.


Simplicef film-coated Tablets are provided in 100mg and 200mg strengths. Zoetis pharmaceutical, a subsidiary of Pfizer Internationals, is a manufacturer of this drug. 


Can Humans Take Simplicef For Dogs?


NO! humans are not allowed to consume veterinary drugs that are used to treat different types of diseases and complications in animals. Although, simplicef generic "Cefpodoxime proxetil" is approved to treat bacterial infectious diseases in both humans and animals. But the brand name "Simplicef (contains cefpodoxime)" is specially formulated for dogs, kittens, puppies, and other small animals. Simplicef 100mg and 200mg tablets are not suitable for humans. 


Most veterinary drugs come with a label "This drug is not suitable for humans"


Cefpodoxime is a broad-spectrum antibiotic that is highly effective against a broad range of diseases caused by bacteria. It can treat all types of soft tissue infections, wounds, abscesses, ear/nose, and eye bacterial infections, STDs (sexually transmitted diseases), and others not described here. 


Why Can't Humans Use Veterinary Drugs?


Humans are not allowed to use animal approved drug brands like Simplicef (by Zoetis pharma), Baytril, Albon, Rilexine, Clavamox, Clavacillin, and Convenia injection, etc. Here, I want to clarify that I am talking about drug brands, that are approved to treat diseases in animals. 


For example, Cefpodoxime proxetil is a chemical composition that is FDA approved to treat bacterial infectious diseases for both Humans and Animals.  


Simplicef contains "cefpodoxime proxetil", but is specifically formulated to use in animals including canine and feline.


Side Effects OR Adverse Reactions


Another critical question is "What happens if humans use veterinary antibiotics?".  As said before, humans are not allowed to use dog antibiotics. If a human administered a veterinary-approved drug, then the following side effects may occur in reaction.


  • Vomiting
  • Nausea
  • Upset Stomach
  • Diarrhea
  • Abdominal cramps and pain.
  • Allergic reactions including skin rashes, irritation, itching, etc.

It's hard to understand like "Why humans want to consume dog antibiotics?". Because most veterinary drug brands are designed to use in animals. For instance, Clavamox (amoxicillin trihydrate_Clavunalate potassium) chewable tablets have pork-liver flavor and are specially formulated for feline and canine. On the other hand, Augmention (amoxicillin trihydrate_clavunalate potassium) is the brand uses for humans. 



Both Clavamox (animals use) and Augmentin (for humans) contain the same generic "amoxicillin trihydrate and clavulanic acid".  But the Clavamox brand is specified to use in animals. The Augmentin brand name is specified for humans.

Friday, August 7, 2020

Simplicef For Dogs | Over The Counter Pets Antibiotic?

Today in the following article, I would tell you How can you buy Simplicef for Dogs Over the Counter? and give you an answer to your question: "Can I Buy Simplicef Without A Vet Prescription?" However, Simplicef (cefpodoxime proxetil) tablets are not over the counter antibiotic drugs. This short but brief article provides a piece of complete information about simplicef medication in dogs, cats, and other small animals.   


simplicef-for-dogs-over-the-counter

Pets, especially dogs and cats are highly vulnerable to develop bacterial infections in their bodies. Bacteria is present everywhere, in air, water, food, soil, and toys, etc. There is a vast type of gram-positive, gram-negative, aerobic, and anaerobic bacteria present in our environment. They may get into the dog's body through the air (during inhalation), eating contaminated foods/uncooked food, drinking contaminated water, and playing with contaminated toys and in soil, etc. 


Commonsels Bacteria In Dogs


There is another type of bacteria that lives in almost all living bodies without causing any harm or infection. These types of bacteria are called "Commensals Bacteria", as they usually help our body in many metabolic processes. For example, commensals bacteria that are present in a dog's digestive system help indigestion. 


Commensals bacteria are present in dog's bodies, in a controlled amount. The body's immune system controls its replication and suppresses their growth to avoid their abnormal or unnecessary over-growth.

bacterial-infection-in-dogs

Bacteria present outside the body or inside the body (commensals bacteria), both can cause a bacterial infection in dogs. It mostly depends on the dog's immune system.  If a dog's immune system gets suppressed due to any reason, i.e. malnutrition, using corticosteroids, etc, then the abnormal overgrowth or over-population of commensals bacteria may lead to a bacterial disease.


If a body's immune system is unable to control over-population, over-replication, or overgrowth of bacterial cells. Then certain types of antibacterial (anti, means "against" and bacterial means "bacteria") drugs are used to control their overgrowth and the infection caused by them.


Antibiotic Types


 Antibiotics are classified in different families, like cephalosporins, quinolones, macrolides, and penicillin-type antimicrobial drugs. Each family provides a huge range of chemical substances that are used to kill or restrict bacterial overgrowth.


Over The Counter Antibiotics


Many folks search on the internet to find antibiotic drugs without a valid prescription. Maybe they do that to avoid a veterinarian fees or due to another reason. But one thing, I want to clarify that all antibiotics are prescription drugs. They sold out on a valid healthcare practitioner prescription only. So you can't buy antibiotic drugs like Simplicef 100mg or Simplicef 200mg tablets without a vet prescription. 


Why Can't I Buy Simplicef For Dogs Over The Counter?


This is because unnecessary use of anti-bacterial drugs may cause antibiotic resistance in the body. Antibiotic resistance is explained as the bacteria may develop resistance against certain types of antibiotics (if used unnecessary or more often without vet guidance). Then more powerful and strong antibiotics are needed to treat infectious diseases for that particular patient.


Simplicef generic is "Cefpodoxime proxetil", which belongs to the cephalosporin class of antibiotics. Cephalosporins kill bacteria by disrupting their cell walls. Cefpodoxime proxetil is a third-generation cephalosporin drug, that is highly effective against all types of soft tissue infections including skin bacterial diseases, urinary tract bacterial diseases, ear/eye and nose infection, tooth infection, sore throat and others not described here. 


It's an FDA approved veterinary drug, manufactured by Zoetis pharmaceutical private limited company. It's very famous due to its effectiveness and positive reviews.


Summary


Simplicef film-coated tablets are FDA (Food and Drug Administration) approved veterinary broad-spectrum antibiotic drugs used to treat bacterial infections in dogs, cats, and other small animals. Like any other antibiotic, these antibacterial tablets also need a valid veterinarian prescription to buy them online or a local drugstore. Simplicef is not over the counter (OTC) medicine. It needs a valid prescription because it's a prescription drug. 

Thursday, August 6, 2020

Is Simplicef A Sulfa Drug? Cefpodoxime Proxetil Medication

It's very important to know that "Do Simplicef tablets belong to the sulfa group (sulfonamide group of drugs) or not". Because a pet who has sulfonamide allergy may get serious side effects or adverse reactions by using Sulfa-drugs medication. The common adverse reactions may include swelling or inflammation of face or any other part of the body, skin rashes, difficulty in breathing, hot spots, etc. In the following article, I would answer all of your queries related to this topic. 

Quick Answer: Is Cefpodoxime Proxetil A Sulfa Drug?

is-simplicef-a-sulfa-drug

NO! simplicef (cefpodoxime proxetil) does not belong to sulfonamides. A dog with sulfa-allergy can use simplicef medication to treat a variety of bacterial diseases including skin infections, bladder infection, all types of soft tissue infections, etc. It's an FDA (Food and Drug Authority) approved antibiotic drug used to kill a broad range of gram-negative as well as gram-positive bacteria that contains a cell wall. 

Because cefpodoxime proxetil is a cephalosporin drug. Cefixime, cefuroxime, cefprozil, cefepime are some common examples of cephalosporins. They kill or restrict the growth of bacteria by disrupting their cell walls. Hence, they stop bacteria from replication. Simplicef can be used against bacteria that have a cell wall. 

Antibiotics do not treat viral or parasitic infections. However, they can be used to treat secondary bacterial infections caused by viruses, parasites, and insect bites.

What is a Sulfa Group or Sulfonamide Group?


Chemical compounds that contain sulfur dioxide (SO2) attach with one or two amine groups (NH-H) are called sulfa-compounds and the drugs are known as sulfonamides. 

a-sulfa-group-chemical-structure
Here are some examples of sulfonamides contain a sulfa group in their chemical structures.

1. Co-trimoxazole or Sulfamethoxazole_Trimethoprim Combination (antibiotic_sulf drug)

co-trimoxazole-structure-with-sulfa-group


2. Furosemide (diuratic_sulfonamide)

furosemide-chemical-structure-with-sulfa-group


3. Gliclazide (diabetic_sulfonamide)

gliclazide-structure-with-sulfa-group


So you can see that all of the above chemical structures contain a sulfa group present in their structure. While you can also see that cefpodoxime proxetil chemical structure does not have a sulfonamide group. Below is the cefpodoxime proxetil chemical structure;

cefpodoxime-proxetil-chemical-structure-without-sulfa-group


Summary


Simplicef chemical structure shows that there is no sulfa group present. So if someone is confused about a question, "Is Simplicef a Sulfa drug or Sulfonamide?" Then he/she must read the above article carefully. Because this article explains that Simplicef (cefpodoxime proxetil) does not belong to sulfonamide drugs. A dog or other animal with sulfonamide allergy can use this antibiotic drug to treat infectious diseases caused by bacteria (that contain a cell wall). 

Because this drug kills bacterial cells by disrupting their cell walls. Bacteria who lack a cell wall cannot be treated with this drug. So always consult a veterinarian before taking any kind of medication for your pets. However, cefpodoxime proxetil is a prescription drug that is only available on a registered veterinarian prescription only.

This chemical substance is safe to use in dogs, cats, and other small animals by the recommendation of a veterinarian. It's recommended dose varies between 2.3milligrams to 4.5 milligrams per one pound (bodyweight). A vet may suggest the exact dosage plan for your pet after diagnosing the bacteria-type and the severity of an infection. If you have any further queries in your mind, feel free to ask. All you need is just comment below.

Wednesday, August 5, 2020

Can I Give My Dog Benadryl With Simplicef (Cefpodoxime)?

Today in the following article, I decided to discuss two highly effective drugs Simplicef and Benadryl, their benefits, dosage, interactions, and side effects for dogs, cats, and all types of canine and feline species. Simplicef is an antibiotic while Benadryl is an anti-allergic or anti-histamine medication. It's important to know about their indications, interactions, and dose to avoid serious complications.


Simplicef is the trademark of the Pfizer pharmaceutical company. Its generic name is Cefpodoxime proxetil, which belongs to the cephalosporin class of antibiotic drugs. Cephalosporins treat bacterial infections by stopping the mechanism of cell wall synthesis of bacterial cells. So, they are effective against almost all types of gram-positive and gram-negative types of bacteria.


simplicef-and-benadryl-together-for-dogs

If a dog has developed a bacterial infection of the skin, urinary tract, nose/eye, or ear, etc. Then, you don't need to worry because the cefpodoxime proxetil medication can treat all kinds of infectious diseases in dogs (caused by bacteria that contain a cell wall).


Benadryl on the other hand used to treat allergic reactions in dogs and other living organisms. It contains a chemical ingredient called "diphenhydramine" which is used to treats skin rashes, runny nose, pain, itching, burns, and other allergic conditions.


Simplicef and Benadryl Together For Dogs


But the question is "Can We Use Simplicef And Benadryl Together?". So, the answer is a little complicated because there are not any side effects or adverse reactions found when the cefpodoxime proxetil and diphenhydramine are given together. But to avoid drug interaction, it is advised that you should never use them together in the following cases described below;

  • In pregnant dogs, it is suggested to avoid taking cefpodoxime and diphenhydramine medication together. But a veterinarian may take a decision whether it is necessary or not. 
  • Nursing or lactating dogs.
  • Dogs with a history of kidney disease.
  • A dog with any liver illness.
Although, both drugs are FDA approved and can be used in dogs together. A veterinarian may decide whether to prescribe them together or not. But it's suggested to avoid them during the pregnancy period, lactation and others shown in the above list. If you're using Simplicef and Benadryl together for your dog, then there should be, at least, one hour difference between their doses.

What Does Benadryl Treats In Dogs?

Benadryl contains an anti-histamine drug called "Diphenhydramine Hydrochloride". This drug helps to treat all kinds of allergic reactions in dogs. It can provide relief from the following conditions;

  • Itching 
  • Skin rashes
  • Burns
  • Itching due to insect bites
  • Insect bites allergic reactions like rashes, itching, hair loss, etc
  • Heat rashes (as it is also available in topical cream/spray form)
  • Runny nose
  • Hives
  • Nasal congestion
  • Sneezing
  • Swelling or inflammation 
  • Redness of skin
It can also be used other allergic reactions that are not described above. Your dog's veterinarian would decide whether to use it or not. It does not treat bacterial infections or kill bacteria. You have to take an antibiotic drug if your dog has developed any type of bacterial infection.

Availability

Benadryl (diphenhydramine HCl) is available for your dog in the following forms;

  • Topical cream
  • Topical spray
  • Chewable tablets
  • Liquid oral suspension
  • Cooling gel form to prevent itching instantly
  • Itch relief stick form

Dosage

If you want to know the ideal dosage plan for your dog for itching, skin rashes, runny nose, or any other allergic reaction. You have to consult your veterinarian. Because it's a prescription drug and is not available without a valid veterinarian prescription. 

However, you can use Benadryl extra strength cooling gel, stick, and topical cream or spray for your dog. You have to just apply an adequate amount of cream/spray/gel on the affected area. But when we talk about chewable tablets or liquid suspension or drops, you have to ask your veterinarian. 

Side Effects Or Adverse Reactions


However it's a highly tolerable drug, but may not suitable for some dogs. The dogs who are hypersensitive to diphenhydramine or other anti-histamine drugs i.e, loratadine, etc should avoid this drug. Immediately stop using this drug, if you see the following adverse reactions after consuming;

  • Vomiting
  • Diarrhea
  • Nausea
  • Upset stomach
  • Abdominal pain
  • Constipation
  • Abdominal cramps
  • Loss of appetite (anorexia)
  • Increased thirst or drinking more water
  • Change in behavior i.e, aggressiveness, barking, anxiousness, etc
Usually, diphenhydramine does not show adverse reactions but if you see any of the above by using this drug, immediately re-visit your dog's veterinarian and consult about the situation. 

What Does Simplicef Treats In Dogs?


It contains an antibacterial ingredient called "Cefpodoxime proxetil" that is a third-generation cephalosporin, a strong antibiotic drug, that is FDA (Food and Drug Administration) approved drug to treat a broad range of bacterial diseases in pets

It's available in film-coated tablets, which is provided in two strengths i.e, 100mg and 200mg.  A veterinarian may suggest the ideal dose for a dog but 2.3milligram to 4.5milligram per one pound (lb) is the recommended dose for dogs.

Cefpodoxime can be used to treat the following problems;

  • Urinary tract infections including bladder, ureters, urethra, and kidneys infection caused a bacterial accumulation.
  • Bacterial infections of the nose, ear, and eyes
  • Periodontal disease (swollen gums or other dental infections)
  • Sore throat
  • Skin bacterial diseases including folliculitis, cellulitis, pyoderma, and others.
  • Paw infection 
  • All types of soft tissue infections
  • Wounds
  • Abscesses
  • Burns
  • Secondary infections caused by viruses, parasites, and insect bites.

Summary


You can give your dog Benadryl (diphenhydramine HCL) with simplicef (cefpodoxime proxetil) together but avoid if your dog is pregnant, nursing or lactating, or has a history of kidney or liver ailment. Diphenhydramine (anti-allergy drug) treats all types of allergic conditions in dogs including itchiness, burns, skin rashes, runny nose, sneezing, and others not described here. Simplicef contains an active ingredient "cefpodoxime proxetil", which is an antibiotic drug, which is effective against a broad range of gram-positive and gram-negative types of bacteria. Both cefpodoxime and diphenhydramine can be used together to treat bacterial and allergic problems in dogs, cats, and other small animals.

Sunday, August 2, 2020

Alternative To Simplicef for Dogs | Cefpodoxime Alternatives

Broad-spectrum antibiotics are used to treat bacterial infections in living organisms including humans, animals, and birds. Anti-bacterial (anti means against, and bacterial means bacteria/germs) medicine are differentiated in classes, like cephalosporins, macrolide antibiotics, quinolones, penicillin, etc. Some antibacterial drugs kill bacteria by disturbing the mechanism of bacterial cell wall synthesis and others (like metronidazole) work by restricting the bacterial over-growth or over-replication. 

Simplicef belongs to the cephalosporin class of antibiotics. It contains an active ingredient called Cefpodoxime proxetil. Cephalosporins are the best beta-lactam antibiotics that kill or control bacterial growth by disrupting the bacterial cell wall. 
This article is just for the information purpose only. We don't suggest or recommend any medication or brand. Consult your dog's veterinary doctor before taking any kind of medicine for your pet. 
alternative-to-simplicef-for-dogs

Cefpodoxime, a strong antibiotic drug, is used to treat all kinds of bacterial infectious diseases including nose infection, eye infection, bladder infection, kidneys bacterial diseases, liver, ear, stomach, skin, wounds, abscesses, periodontal diseases, and other soft tissue infections that are not described here.

This is a highly effective composition against bacteria, who has a cell wall. It does not work against bacterial infections caused by cytoplasmic or mycoplasmic bacteria that do not have a cell wall. However, Simplicef film-coated tablets are effective against a broad range of gram-positive and gram-negative types of germs. 

In the following article, I decided to share some of the simplicef alternative brand names that the veterinarians are prescribing for dogs, cats, and other small animals in the United States of America.

Simplicef is a Zoetis pharmaceutical product, the company has also provided many other best veterinary antibiotics for animals, e.g, Zeniquin (marbofloxacin).  It's an FDA approved antibiotic drug for dogs. 2.3 milligrams/pound to 4.5 milligrams/pound is the recommended dose for cefpodoxime in canine. 

Bantan and Vantin are the same alternative brand names to simplicef for dogs. But if you're looking for the best alternative broad-spectrum, highly effective, most prescribed for dogs antibiotics, then you must read the below section.


Best Cefpodoxime Alternatives For Dogs


Below is the list of alternatives veterinary antibiotic drugs used to treat bacterial infectious diseases in puppies, kittens, all dog breeds, and other small animals. 

  • Clavamox (contains amoxicillin trihydrate and clavulanic acid) Chewable tablets, liquid oral suspension, and drops. 
  • Zeniquin (contains marbofloxacin) Tablets, a fluoroquinolone antibiotic drug, effective against a variety of gram-positive and gram-negative bacteria.
  • Baytril (contains enrofloxacin) Tablets, a fluoroquinolone (strong) antibiotic, used to treat all types of bacterial diseases.

Topical Antibiotic Creams For Dogs


  • Neomycin/Polymyxin B topical cream and ointment uses to treat all kinds of wounds, and bacterial skin infections.
  • Bacitracin topical ointment.
  • Mupirocin antibacterial cream for dogs.
  • Fusidic acid 2% cream and ointment for topical bacterial infections.
  • Clindamycin cream.
  • Chlorhexidine topical application. 

Cephalosporins For Dogs


Not all cephalosporins are FDA (Food and drug administration) approved to treat infectious diseases caused by bacteria in small animals like dogs and cats. Cefpodoxime proxetil is FDA approved cephalosporin veterinary antibacterial composition to treat a broad range of bacterial diseases in dogs. Below is the list of cephalosporin drugs that may be used as Simplicef alternatives for dogs;

  • Cefuroxime
  • Cefixime
  • Cefepime
  • Cefadroxil
  • Cephalexin (Brand name: "Rilexine", FDA approved drug for dogs)
All antibiotics are prescription items. They need a valid veterinary prescription to buy online or from your local drugstore. Unncesessary usage of antibacterial drugs may cause antibiotic resistence in the body. Antibiotic resistence is harmful. 

List Of Most Prescribed Antibiotics For Dogs


Below is the list of most prescribed antibacterial medicine used to treat infectious diseases in dogs and cats by the veterinarians. Antibiotics are chemical substances used to treat bacterial infections only. They do not treat viral infections like influenza. They may also be used to treat secondary bacterial infections caused by viruses, parasites, and insects.  
  • Penicillin
  • Doxycycline Hyclate
  • Sulfamethoxazole_Trimethoprim
  • Amoxicillin
  • Ciprofloxacin
  • Metronidazole
  • Gentamycin
  • Orbifloxacin
  • Chloramphenicol
  • Pradofloxacin
  • Ampicillin
  • Florfenicol

Summary:


Vantin is the same alternative brand name to simplicef for dogs if you're looking for the same ingredient i.e, "Cefpodoxime proxetil". Simplicef Tablets belong to the cephalosporin class of antibiotics. Cefepime, cefixime, cefprozil, cephalexin, cefadroxil are some examples of cephalosporin drugs. Every living body is different from others. Usually, antibiotics like Simplicef are highly tolerated by the dog's body. But in some cases, they can show side effects or adverse reactions. 

Always consult your dog's veterinarian before buying any medicine for your pet. Antibiotics are not over the counter drugs. They are prescription specified. It means you need a valid prescription to buy antibiotics for dogs online or from your local pharmacy. It is because more often and unnecessary use of antibacterial medicines may cause antibiotic resistance which is harmful and may cause life-threatening consequences.
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