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Apoquel medication is famous for treating certain skin disorders, i.e. itching, irritations, dermatitis, rashes, inflammation or swelling, redness, and other signs of allergies in dogs.

This is an FDA (Food and Drug Administration) approved (veterinary) medicine that contains the active substance, “Oclacitinib maleate” which belongs to immune system modulator drugs.

In the following piece of the article, I am going to answer your questions i.e. Is Apoquel Safe for Humans?Does Apoquel cause side effects in humans?

What exactly is Apoquel?

Apoquel (oclacitinib) is a medication veterinarians use to treat itching and inflammation that are caused by allergic skin-conditions in dogs, such as atopic dermatitis.

Apoquel is a Janus Kinase (JAK) Inhibitor – which means it blocks the activity of some specific proteins that are called “JAKs”  Thes JAKs  are involved in the inflammation process; by blocking these proteins, Apoquel reduces the symptoms of itching and inflammation associated with allergic skin conditions.

Apoquel is available in tablet form and is  usually administered twice a day – with or without some dog food. The dosage and the length of treatment will depend on the severity of the condition- and the response to this medication.

It’s also very important to note that Apoquel should only be used under the guidance of your veterinarian and should not be used in dogs with certain medical conditions such as certain types of infections; or if a dog is pregnant or lactating.

Apoquel is not a cure for the underlying allergy of your Dog – it is only a symptomatic treatment that can provide relief from itching. If you want to find out more information about your Dog`s allergy, or you have any other concern about your dog’s health –  you should consult with your veterinarian.


Can Humans take Apoquel? 

Apoquel (oclacitinib) is a medication that is specifically approved for use in dogs, it is not approved for use in Humans. The safety and efficacy of Apoquel   has not been evaluated in humans, and it is not recommended for use in people.

It is not safe for human consumption, and taking any medication that is not prescribed for you by a medical professional can be dangerous and may have serious side effects. Please consult a qualified healthcare professional if you are experiencing symptoms of an allergic condition.

No studies have been performed on Apoquel 16mg tablets for humans yet. Although, it’s not recommended for humans to take oclacitinib maleate.

Possible Side Effects of Apoquel on Humans

As said before, no clinical studies have been taken in humans for this medication. However, using this immune system modulator drug in humans may show up life-threatening and fatal consequences.

Some of the potential effects in humans are;

  • Upset stomach
  • Digestive system disorders
  • Gas, bloating, or flatulence
  • GERD (gastroesophageal reflux disease)
  • Ulcers in the esophagus, intestines, and stomach
  • Diarrhea
  • Vomiting & nausea
  • Constipation
  • Increased risks of bacterial/fungal/viral infections
  • Loss of appetite and increase in thirst
  • Itching, skin irritations, and rashes
  • Redness, swelling, or inflammation
  • Hives and hair loss

Apoquel medication suppresses the defense system of a body and reduces white blood cells. It may cause unwanted consequences including cancer.

Apoquel Equivalents for Humans

Cyclosporin is the best example of an immune system suppressant drug in humans. However, Sandimum Neoral (cyclosporin) medication does not recommend by the doctor for treating allergies or other skin disorders.

In this section, I am going to share the list of best medicines or Apoquel alternatives for treating the symptoms of allergies.


It is an antihistamine drug that is used for the treatment of all kinds of allergic reactions in humans. It can be used to relieve the signs or symptoms of seasonal allergies (runny or water nose, sore throat, itching, cold, & flu, etc), dermatitis (inflammation or swelling on the skin), etc.

The recommended dose of Cetirizine drug in humans is 10mg once daily. It’s available At the counter (OTC) without a veterinarian prescription while you need a valid prescription for buying Apoquel for pets.


Another best treatment for human allergies and the symptoms of allergic reactions includes swelling (or inflammation) on the skin, rashes, redness, itching, irritations on the skin, feet, ears, etc.

It’s available in two different strengths, i.e. 10mg, 20mg, respectively. However, you don’t need a prescription for buying this medicine. It’s a highly effective second-generation antihistamine drug.


This is an FDA (Food and Drug Administration) approved drug used for treating all kinds of adverse reactions in humans.

It treats swelling or inflammation on the skin, skin irritations, itching, breathing difficulty, and other symptoms of allergies in humans. Consult your doctor before taking any kind of medicine.

This article is just for information purposes only. We don’t recommend or suggest any kinds of drugs (medications). Unnecessary use of antibiotics/antiviral/antifungal/or anti-allergy drugs may cause fatal consequences.

You may like to read: Can garlic kill a dog?

Doctor Xeeshan

Doctor Xeeshan

I am Doctor Xeeshan, located in Lahore, Punjab, Pakistan. In this blog, I am providing authentic information about dog breeds, diseases, medications, etc.


Anonymous · December 10, 2022 at 6:34 am

I aaccidentally took one half of apoquel 5.4 tablet. What will happen to me?

Anonymous · December 10, 2022 at 6:34 am

I accidentally took one half ofApoquel 5.4 tablet. What happens to me?

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