If a veterinarian has prescribed amoxicillin trihydrate and clavulanate potassium for your dog then it means your pet has developed a bacterial infection in its body that should be treated with an antibiotic drug. Basically, Amoxicillin trihydrate is an antibiotic drug, which is a beta-lactam anti-bacterial formulation and is a penicillin-type antibiotic.

Within the following article, I tried to answer all the questions that may be raised in your mind. Like, What is the side effects of using amoxicillin trihydrate and clavulanate potassium (clavulanic acid) for dogs? or What are the amoxicillin trihydrate and clavulanate potassium dosage for dogs? etc.


Why Amoxicillin Trihydrate and Clavulanic Acid is prescribed for dogs?

You may get this preparation by the brand name of “CLAVAMOX” at your local pharmacy. Clavamox is the Zoetis pharma product that contains amoxicillin trihydrate and clavulanate potassium. It is provided in pork liver-flavored tablets, oral suspension, and oral drops form for canines and felines. This preparation treats a variety of infectious diseases caused by gram-positive, gram-negative, and other types of bacteria.

Clavamox (amoxicillin and clavulanic acid) is the FDA (Food and Drug Administration) approved drug to treat bacterial infections in animals like canines and felines. It’s available on a registered veterinarian prescription only

Amoxicillin trihydrate and clavulanic acid (clavulanate potassium) preparation is prescribed by the veterinarians to treat a variety of bacterial diseases included;

  • Periodontal disease
  • Soft-tissue infections
  • Urinary tract infections
  • Wounds
  • Abscesses in dogs
  • Cellulitis 
  • Kennel Cough in dogs
  • All types of skin diseases caused by bacteria (single=bacterium)
  • Eye infections
  • Ear infections
  • Nose Infections
  • Septicemia (blood poisoning) caused by bacteria
  • small intestines or large intestines infection

and other infectious problems that are not listed above.

What exactly is Amoxicillin Trihydrate?

Amoxicillin trihydrate is a type of antibiotic medication. It is used to treat infections caused by bacteria. It belongs to a group of medications known as penicillins, which work by inhibiting the growth and multiplication of bacteria.

Amoxicillin trihydrate is effective against a wide range of bacteria, including those that cause infections of the respiratory tract, urinary tract, skin, and ears.

It is also used to prevent infections in people who are at high risk of developing infections, such as those with compromised immune systems or those undergoing certain medical procedures. Amoxicillin trihydrate is usually taken by mouth in the form of a capsule or a liquid.

It is generally well-tolerated, but like all medications, it can cause side effects in some people. It is important to take amoxicillin trihydrate as directed by your healthcare provider and to finish the entire course of treatment to ensure that the infection is completely cured.

How long does it take for amoxicillin to work in dogs?

What exactly is Clavulanic Acid?

Clavulanic acid is a beta-lactamase inhibitor, which means that it helps to prevent certain bacteria from breaking down the antibiotic medication that is being used to treat the infection. It is often used in combination with other antibiotic medications, such as amoxicillin, to increase the effectiveness of the treatment.

Clavulanic acid works by blocking the action of beta-lactamase, an enzyme produced by certain bacteria that can inactivate certain antibiotics. By inhibiting the action of this enzyme, clavulanic acid helps to protect the antibiotic from being inactivated and allows it to be more effective at killing the bacteria.

Clavulanic acid is often used to treat infections caused by bacteria that are resistant to other types of antibiotics.

It is available in the form of a tablet or a liquid and is usually taken by mouth. Like all medications, clavulanic acid can cause side effects in some people. It is important to take clavulanic acid as directed by your healthcare provider and to finish the entire course of treatment to ensure that the infection is completely cured.

Clavulanic Acid Explained

Guide to Amoxicillin Trihydrate and Clavulanate Potassium Dosage for Dogs

Amoxicillin trihydrate and clavulanate potassium is a powerful antibiotic combination often prescribed to dogs. It’s important to provide the right dose based on your dog’s weight to ensure its effectiveness while maintaining safety. Here’s a more detailed breakdown:

  • Available Strengths: The medication comes in four distinct potencies:
    • 62.5mg
    • 125mg
    • 250mg
    • 375mg
  • Brand Name: In the United States, you might know this antibiotic combination by its popular brand name, Clavamox.
  • Dosage by Weight: While it’s always essential to consult with a veterinarian, a dosage plan based on your dog’s weight will help in treating various illnesses.

Amoxicillin Trihydrate And Clavulanate Potassium Tablets For Dogs – Dosage for Dogs by Weight

05 lb62.5 mg Half tablet (31.5mg) in a day
10 lb62.5 mg once daily
15 lb62.5 mg tablets 1 and a half (93.75mg) daily
20 lb62.5 mg tablet twice daily or 125 mg once a day
25 lb125 mg + 31.25 mg tablet once daily (156.25 mg)
Dosage of Amoxicillin Trihydrate And Clavulanate Potassium Tablets For Dogs

So, above is the researched base recommended dose for amoxicillin trihydrate and clavulanate potassium (clavulanic acid) for dogs. If you want to know about the exact dosage by your dog weight then comment below and get an instant reply from me.

A veterinarian may suggest the best dosage plan for treating different kind of bacterial infections after diagnosing the infectious bacteria type and by observing the patient condition. We don’t suggest or recommend any medication or dosage plan. This all is 100% authentic information just for your knowledge.

Always consult your veterinary doctor before giving any kind of medicine to your dog or cat. 

Amoxicillin trihydrate and Clavulanic Acid Side Effects in DOGS

Although, this is a very tolerable drug by the animals. But for some of them, it may cause some rare to serious adverse reactions. Especially for those dogs who already have other problems of kidney, heart, or stomach, etc. Clavamox or amoxicillin trihydrate and clavulanate potassium side effects in dogs include;

  • Upset stomach
  • Diarrhea
  • Abdominal pain
  • Skin rashes (redness on the skin)
  • Swelling of the jaw
  • Vomiting
  • Nausea
  • Behavioral changes
  • Lethargy
  • Loss of appetite

above are some common adverse reactions that may occur, if your dog’s body is hypersensitive to any penicillin-type antibiotics. Immediately discontinue the drug and seek medical help, if your dog has any of the above side effects following the amoxicillin trihydrate and clavulanic acid (clavulanate potassium) treatment.

Overdosage of CLAVAMOX

CLAVAMOX is the brand name for a combination of amoxicillin and clavulanic acid, which is used to treat certain bacterial infections. If you have taken an overdose of CLAVAMOX, you should seek immediate medical attention. Symptoms of an overdose may include:

  • Nausea and vomiting
  • Diarrhea
  • Stomach pain
  • Rash or hives
  • Difficulty breathing or swallowing
  • Swelling of the face, lips, tongue, or throat

If your dog is experiencing any of these symptoms or you believe your dog may have an overdose of CLAVAMOX, you should call your healthcare provider or a poison control center right away.  You must listen to your dog’s veterinarian follow up instructions carefully.

Especially, the dosage plan a Vet has set for your pet. This is because the amoxicillin trihydrate and clavulanate potassium overdosage may result in chronic health problems for your dog. 

Although, in the case of overdosage, instantly seek medical help for your pet.

Anyone, who has more questions related to this topic or someone who is still confused about using CLAVAMOX (Amoxicillin trihydrate and clavulanate potassium) in dogs.

He/She can ask the questions in the comment box. You should also be aware of:

Why amoxicillin trihydrate used in combination with clavulanate potassium to treat bacterial infections in dogs?.  

Read also:

Doctor Xeeshan

Doctor Xeeshan

I am Doctor Xeeshan, located in Lahore, Punjab, Pakistan. In this blog, I am providing authentic information about dog breeds, diseases, medications, etc.


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