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Can Benadryl treat separation anxiety in your dog? There are some precautions to consider before deciding to give Benadryl to your dog. Benadryl tablets aren’t for every dog and can cause serious side effects. 

A dog weighing up to 50 pounds can safely take two 25mg tablets. A severe allergic reaction can cause facial swelling and difficulty breathing, so you should seek help from your veterinarian if your dog is experiencing such symptoms.



How Can Benadryl Help Dogs with Separation Anxiety?

The sedative effects of Benadryl may help calm a stressed dog. If you want to alleviate the problem, consult a veterinarian. 

While Benadryl is relatively safe for dogs, some breeds can develop resistance to the drug. It can also take half an hour to take effect. Other medications are also effective for anxiety in dogs.

Benadryl Dosage for Dogs with Separation Anxiety

To treat your dog’s separation anxiety, consider giving your dog a Benadryl dosage. These pills are very effective for treating allergies in dogs, and the most common dosage is two mg per kilogram of body weight

As with humans, the correct dosage depends on your dog’s weight, age, and current medications. Always give your dog Benadryl only in the recommended dosage, and report any reaction to your veterinarian.

While the dosage for dogs with separation anxiety is different from the dosage for humans, it is safe to administer it at home with the supervision of your veterinarian.

Benadryl comes in tablets of 25 mg and 50 mg. You should cut the tablets into small pieces to make the dosage easier to administer to your dog. 
For a 50-pound dog, a single tablet contains approximately eight milligrams, and you should administer it two to three times a day.

Separation Anxiety in Dogs?

If your dog is experiencing excessive separation anxiety, you need to seek professional help.

Although many symptoms of separation anxiety are similar to medical conditions, your veterinarian can determine if your pet is suffering from a true condition. 
Moreover, the early treatment of separation anxiety is essential in ensuring your pet’s comfort and adaptability. 
However, if you are unable to find an appropriate treatment plan for your dog, follow some guidelines to help you help your pet manage his or her anxiety.

Signs and Symptoms of Separation Anxiety in Dogs

Symptoms of separation anxiety include destructive behavior, which is usually located around exit and entry points. 
During periods of elevated anxiety, your dog may attempt to escape, causing damage and costly veterinary treatments. 
In addition to destructive behaviors, separation anxiety may lead to bowel and bladder problems. 
A vet should be consulted immediately if you notice new symptoms. Even if your dog seems perfectly healthy, medical tests are still necessary to rule out the possibility of a medical cause.
signs and symptoms of separation anxiety in dogs

The signs and symptoms of separation anxiety in dogs vary from one dog to another but are usually present within the first 10 minutes.

If you notice these behaviors during this time, consult a veterinarian. Dogs with separation anxiety may also exhibit symptoms of other medical conditions, including problems with their bowel and bladder
Keeping these issues in mind may help you identify the problem and treat it accordingly. Here are the signs and symptoms of separation anxiety in dogs.

Your dog may only act out when you leave the house on a specific day. However, if it always acts up when you leave, this may indicate a medical condition or need to be trained.

If your dog has excessive energy and often whimpers, this may be a sign of a medical condition. However, true separation anxiety in dogs usually begins before you leave the house. 
If you are going to leave for work or school, prepare your dog for the time when you are gone. Try to schedule playtime for your dog before you leave. 
If your dog has a favorite treat, offer it to keep him busy while you’re gone.

Best Medicines to Treat Separation Anxiety in Dogs

There are a number of medications available to treat separation anxiety in dogs. The first approved medication is Clomicalm, which has a fast onset of effect and can take up to eight weeks to have its full effect. 

These medications are sometimes used off-label, but you should always consult a veterinarian if your pet is experiencing severe separation anxiety symptoms. 
Fortunately, there are several different types of medications to choose from.

Fast-acting medications can be used for a few hours at a time, while long-term medications take several hours to work.



The fast-acting medications, such as Valium(r), are often used until other, more permanent treatments are tried. 
One such medicine is diazepam, which causes a sedative effect within a few hours of separation. 


Alprazolam is a similar drug but lasts longer. Because it is a controlled drug, it may require paperwork and a license. 
You may also have to be careful with the dosage as local laws limit the number of tablets prescribed.


Another type of medication is amitriptyline. This tricyclic antidepressant is often prescribed to treat separation anxiety in dogs. 
It works by increasing serotonin levels in the brain. Amitriptyline is available in spray, liquid, and tablet forms. 
The long-acting version should be given to dogs who are left alone on a regular basis. 
Medications for separation anxiety in dogs should be tapered off gradually so as not to have the risk of relapse.

Doctor Xeeshan

Doctor Xeeshan

I am Doctor Xeeshan, located in Lahore, Punjab, Pakistan. In this blog, I am providing authentic information about dog breeds, diseases, medications, etc.


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