One question many pet owners have is, does metronidazole treat tooth infections? It may sound simple, but the answer may surprise you. The short answer to this question is, Yes, metronidazole can be used to treat certain dental infections in dogs, cats, and humans. 


Keep in mind that metronidazole is not an FDA-approved drug (for dogs) and is used as an extra-label medication for the treatment of tooth infection in pets. Usually, it is used with other drugs to restrict the growth of germs & to reduce the inflammation of the gums.

In this article, we’ll explain the mechanism of action of the drug and how it works in dogs.

There are side effects associated with the medication. However, they are mild compared to the risks of metronidazole for dogs. You should never give this medicine to a dog if it’s pregnant, or the liver or immune system is damaged.

How to Prevent & Treat a Dental Infection in Dogs?

To prevent this condition in dogs, veterinarians may recommend professional cleaning and extraction of the caudal teeth. 

However, this treatment is not always effective in achieving clinical remission. In some cases, a veterinarian may suggest that you remove the entire tooth. 

The remaining teeth may be extracted as well. A dog that’s missing a tooth may still be able to eat and live a normal life, but it will have a protruding tongue.

Metronidazole Risks and Benefits in Dogs

A 14-day course of metronidazole had significant effects on the gut microbiome of dogs. The bacteria referred to as Fusobacteria (Fu) were reduced in number in the gut of half of the dogs treated. 

The overall richness of bacteria in the gut decreased as well. This was not a temporary effect, however, and the vets recommend the careful use of metronidazole for dogs.

While metronidazole is not FDA-approved, it is frequently prescribed by veterinarians for inflammatory bowel disease and diarrhea. 

The drug is not safe for dogs in their reproductive years, especially if they are pregnant or breastfeeding, because metronidazole can pass into breast milk and harm the young puppies.

Additionally, metronidazole can be harmful to pregnant dogs and to humans who happen to come into contact with it.

Best Antibiotic Treatment for Tooth Infection in Dogs

When it comes to antibiotics for dog teeth infections, metronidazole is the most common drug prescribed by veterinarians. 

This medication, also known as Flagyl, is effective for many different types of infections, but it has long-term risks and side effects. 

Though antibiotics are important for the treatment of many diseases, they do have risks and are not safe for dogs. 

In addition, if used improperly, they can lead to resistance to the medication. This medication is usually prescribed in conjunction with other antibiotics.

Can Antibiotics Cause Tooth Infection in Dogs?

Another type of tooth infection caused by antibiotics is the paradental ulcer. This is an apical cutaneous ulcer on the right maxillary canine tooth. 

The ulcer tissue contacts the tooth’s surface when the mouth is closed. 

The infection can lead to tooth damage if the wound is left untreated. The treatment is often painful and requires frequent reapplication.

Doctor Xeeshan

Doctor Xeeshan

I am Doctor Xeeshan, located in Lahore, Punjab, Pakistan. In this blog, I am providing authentic information about dog breeds, diseases, medications, etc.


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