Today in the following article, I would tell you How can you buy Simplicef for Dogs Over the Counter? and give you an answer to your question: “Can I Buy Simplicef Without A Vet Prescription?” However, Simplicef (cefpodoxime proxetil) tablets are not over the counter antibiotic drugs. This short but brief article provides a piece of complete information about simplicef medication in dogs, cats, and other small animals.   


Pets, especially dogs and cats are highly vulnerable to develop bacterial infections in their bodies. Bacteria is present everywhere, in air, water, food, soil, and toys, etc. There is a vast type of gram-positive, gram-negative, aerobic, and anaerobic bacteria present in our environment. They may get into the dog’s body through the air (during inhalation), eating contaminated foods/uncooked food, drinking contaminated water, and playing with contaminated toys and in soil, etc. 

Commonsels Bacteria In Dogs

There is another type of bacteria that lives in almost all living bodies without causing any harm or infection. These types of bacteria are called “Commensals Bacteria”, as they usually help our body in many metabolic processes. For example, commensals bacteria that are present in a dog’s digestive system help indigestion. 

Commensals bacteria are present in dog’s bodies, in a controlled amount. The body’s immune system controls its replication and suppresses their growth to avoid their abnormal or unnecessary over-growth.


Bacteria present outside the body or inside the body (commensals bacteria), both can cause a bacterial infection in dogs. It mostly depends on the dog’s immune system.  If a dog’s immune system gets suppressed due to any reason, i.e. malnutrition, using corticosteroids, etc, then the abnormal overgrowth or over-population of commensals bacteria may lead to a bacterial disease.

If a body’s immune system is unable to control over-population, over-replication, or overgrowth of bacterial cells. Then certain types of antibacterial (anti, means “against” and bacterial means “bacteria”) drugs are used to control their overgrowth and the infection caused by them.

Antibiotic Types

 Antibiotics are classified in different families, like cephalosporins, quinolones, macrolides, and penicillin-type antimicrobial drugs. Each family provides a huge range of chemical substances that are used to kill or restrict bacterial overgrowth.

Over The Counter Antibiotics

Many folks search on the internet to find antibiotic drugs without a valid prescription. Maybe they do that to avoid a veterinarian fees or due to another reason. But one thing, I want to clarify that all antibiotics are prescription drugs. They sold out on a valid healthcare practitioner prescription only. So you can’t buy antibiotic drugs like Simplicef 100mg or Simplicef 200mg tablets without a vet prescription. 

Why Can’t I Buy Simplicef For Dogs Over The Counter?

This is because unnecessary use of anti-bacterial drugs may cause antibiotic resistance in the body. Antibiotic resistance is explained as the bacteria may develop resistance against certain types of antibiotics (if used unnecessary or more often without vet guidance). Then more powerful and strong antibiotics are needed to treat infectious diseases for that particular patient.

Simplicef generic is “Cefpodoxime proxetil”, which belongs to the cephalosporin class of antibiotics. Cephalosporins kill bacteria by disrupting their cell walls. Cefpodoxime proxetil is a third-generation cephalosporin drug, that is highly effective against all types of soft tissue infections including skin bacterial diseases, urinary tract bacterial diseases, ear/eye and nose infection, tooth infection, sore throat and others not described here. 

It’s an FDA approved veterinary drug, manufactured by Zoetis pharmaceutical private limited company. It’s very famous due to its effectiveness and positive reviews.


Simplicef film-coated tablets are FDA (Food and Drug Administration) approved veterinary broad-spectrum antibiotic drugs used to treat bacterial infections in dogs, cats, and other small animals. Like any other antibiotic, these antibacterial tablets also need a valid veterinarian prescription to buy them online or a local drugstore. Simplicef is not over the counter (OTC) medicine. It needs a valid prescription because it’s a prescription drug. 

Categories: Simplicef

Doctor Xeeshan

Doctor Xeeshan

I am Doctor Xeeshan, located in Lahore, Punjab, Pakistan. In this blog, I am providing authentic information about dog breeds, diseases, medications, etc.


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