If you’re wondering “Why is Metronidazole prescribed for dogs?” read this article.

This prescription antibiotic is used to treat many kinds of dog infections. However, there are some side effects associated with it, and you should know them before giving it to your pet.

For instance, it may cause diarrhea. It’s important to consult your vet about any side effects. It’s also important to keep an eye on your pet’s bloodwork and overall health during treatment.

Metronidazole for Dogs


Is Metronidazole a Prescription Antibiotic?

When given to dogs, metronidazole should be administered in the doses recommended by your veterinarian. The dose may be higher or smaller than that recommended by your veterinarian. 

Make sure to follow the instructions on the prescription label to the letter. If your dog seems to be improving, do not stop giving the antibiotic before the recommended time. 

In some cases, a veterinarian may prescribe a different antibiotic to cure your dog.

While metronidazole is generally safe, it does have a few side effects that should be discussed with your veterinarian. 

Dangers of Metronidazole for Dogs

If your pet has a history of allergic reactions, it may be dangerous to use this medication on it. Your veterinarian should also be aware of any underlying medical conditions in your dog. 

In addition to metronidazole, your pet should not be given this medication if they have liver or anemia problems, epilepsy, or a nervous system disorder. In rare cases, seizures may occur when your pet consumes too much of this antibiotic.

Metronidazole for Infectious Diseases in Dogs

In the case of infection, metronidazole is a common medication in veterinary clinics. It is increasingly used for conditions outside the gastrointestinal tract

In addition to treating gastrointestinal conditions, metronidazole has also been used to treat dental and bone infections, and even internal abscesses. 

Because metronidazole crosses the blood-brain barrier, it can also work on bacteria in the central nervous system.

Metronidazole Dosage for Dogs

The dose of metronidazole for dogs is five to twenty milligrams per kilogram of body weight, but the exact dose should be determined by your veterinarian. 

Your pet will likely need treatment for at least five days, and in some cases, even a month. Your veterinarian will determine the appropriate dosage for your dog. 

Once you have determined the diagnosis, you will be able to begin the treatment.

Although metronidazole is an effective treatment for diarrhea, it is not without side effects. If your dog develops diarrhea with blood, consult your veterinarian immediately.

Metronidazole Interactions with Other Drugs

Metronidazole is also likely to interact with other medications your pet is taking, including cimetidine, phenytoin, and phenobarbital

Make sure to inform your veterinarian about any new medications you are giving your dog.

Metronidazole for Acute Diarrhea

In some cases, metronidazole treatment for acute diarrhea has been shown to shorten the duration of diarrhea and decrease the fecal culture detectability of C. perfringens. 

Additional research needs to determine the benefits and risks of this treatment for diarrhea in dogs

In the meantime, most dogs experience diarrhea that resolves on its own within a few days. A review of these findings is needed to determine if metronidazole is an effective treatment for diarrhea.

What Kinds of Infections Does Metronidazole Treat in Dogs?

Metronidazole is a powerful antibiotic that is sometimes prescribed for different types of bacterial and fungal infections in dogs

Most of these infections are anaerobic, meaning that the bacteria cannot survive without oxygen. 

However, metronidazole can also be used for a variety of other types of infection, including wounds and cuts in the gums of pets. 

This antibiotic is also used for protozoal infections that are transmitted from pets to humans.

If you’ve ever seen a dog with an infection, you’ve probably been told that metronidazole is a popular treatment for the infection. It works by stopping the growth of some bacteria, including those found in the central nervous system, the spinal cord, and the brain. 

But did you know that metronidazole can also be used to treat bone infections? It works by disrupting the DNA in bacteria. If you’re worried about whether or not your pet is allergic to this medication, ask your veterinarian before giving it to them.

Can Metronidazole Cure Giardia in Dogs?

Flagyl and metronidazole can be given to dogs suffering from Giardia, a protozoan parasite. Giardia can cause vomiting, abdominal pain, and diarrhea. 

The antibiotic is effective against anaerobic bacteria and is usually used in conjunction with other drugs. But, the risk of diarrhea remains, and metronidazole is still an effective medication for bacterial infections.

Metronidazole Side Effects in Dogs

However, metronidazole has many side effects. In addition to causing diarrhea, it has some drug interactions, which means you should inform your vet about all medications your dog is taking before starting metronidazole treatment. 

However, diarrhea may be caused by other diseases, such as inflammatory bowel disease, tumors, and pancreas issues. Other types of antibiotics may also cause diarrhea.

This antibiotic is a strong one and is often prescribed to dogs with various types of infection. It is also used for wound infections and gastrointestinal diseases in dogs. 

Who Can Use Metronidazole for Treating Infections in Dogs?

Although metronidazole is widely used to treat these types of infections, it is not recommended for every dog. Your veterinarian may suggest some alternative treatments for your pet. These are more effective and less expensive. However, they may not work for all dogs.


As with most antibiotics, metronidazole can have harmful side effects when given in excess. A single accidental dose of metronidazole can be fatal for a dog. 

An overdose of metronidazole can cause seizures and neurological problems. While metronidazole is relatively safe for pets, there is still a risk of overdose if your dog accidentally consumes large amounts.

The drug should only be given by a veterinarian or a licensed pharmacy. Although metronidazole has a mildly bitter taste, some dogs may experience side effects. Excessive salivation and drooling, and vomiting are common side effects of the drug. Aside from these, there are also some severe side effects associated with metronidazole.

Research Explains Side Effects of Metronidazole in Dogs

In a study, researchers gave 14-day courses of metronidazole to healthy dogs. More than half developed diarrhea during this treatment. 

Their gut microbiome’s composition changed significantly as a result of metronidazole use.

The microbiome’s overall richness and beneficial bacteria were drastically reduced. These effects are not temporary and may compromise the healthy functioning of the gut. As such, veterinarians should be cautious when prescribing metronidazole to dogs.

Can Metronidazole Cause Diarrhea in Dogs?

The problem with a dog’s stomach lining is that many antibiotics, including metronidazole, kill good bacteria that dogs need for digestion. These drugs also deplete the gut’s overall bacterial diversity, leaving it in a state of imbalance.

In a new study, metronidazole had a dramatic effect on dog gut microbiome diversity, reducing the number of beneficial bacteria and decreasing the overall richness of bacteria.

In some cases, the side effects of metronidazole for dogs are not severe enough to require treatment. 

If you’re concerned, you should follow your veterinarian’s advice and make sure your dog finishes the entire course of treatment. 

Long-Term Effects of Metronidazole

Despite the risks of metronidazole for diarrhea, the antibiotic can clear up the infection and prevent it from coming back. The long-term effects of metronidazole for dogs are minimal and generally resolve on their own.

Metronidazole for Dog Acute Hemorrhagic Diarrhea

While it may temporarily solve diarrhea in dogs, recent studies question the effectiveness of this antibiotic for dogs. 

One clinical trial showed minimal improvement in dogs with acute hemorrhagic diarrhea. The majority of cases of toxicity were associated with high doses of metronidazole rather than long-term smaller doses. 

Despite this, metronidazole for dogs is a common choice for treating diarrhea in dogs.

The side effects of metronidazole for dogs are often mild in the short term, but the effects can worsen over time. If you notice diarrhea, you should immediately take your dog to the veterinarian for further testing. 

If the diarrhea is persistent, give fresh water to your dog to keep him hydrated. There is a slight chance that metronidazole for dogs can cause neurological effects.

Metronidazole Kills Good Bacteria in the Gut

While metronidazole for dogs can cure the symptoms of diarrhea, it can cause serious side effects in your pet. This antibiotic has been linked to the destruction of a dog’s microbiome. This population of bacteria in the gut aids digestion and immune function. 

By reducing the number of good bacteria in the gut, metronidazole can cause diarrhea in your dog. This drug should only be given to dogs suffering from an acute intestinal infection.

Alternative to Metronidazole for Dogs

If your dog has diarrhea caused by bacterial infections, you should consider switching to another antibiotic. Another drug commonly used for diarrhea is Flagyl

Both metronidazole and Flagyl (generic: metronidazole) can cause diarrhea in dogs. If you are unsure, ask your veterinarian for an alternative. It’s safe, but you should consult your veterinarian first to make sure your dog is getting the right dosage for him.

Doctor Xeeshan

Doctor Xeeshan

I am Doctor Xeeshan, located in Lahore, Punjab, Pakistan. In this blog, I am providing authentic information about dog breeds, diseases, medications, etc.


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