Omeprazole, commonly known as Prilosec, is a medication primarily prescribed for humans to treat stomach acid-related issues such as gastroesophageal reflux disease (GERD). However, did you know that it can also be prescribed for our canine companions?

Why is Omeprazole Prescribed for Dogs?

Omeprazole, commonly associated with its brand name Prilosec, belongs to a class of drugs known as proton pump inhibitors (PPIs). These drugs function by reducing the amount of stomach acid produced by the glands in the stomach lining.

What Is Omeprazole Used For Dogs?

This reduction in acid is particularly beneficial for addressing several conditions in dogs:

Treat Stomach Ulcers and Prevent Their Recurrence:

  • Ulcer Formation: Just like in humans, dogs can develop stomach ulcers. These are painful sores that form on the lining of the stomach, upper small intestine, or esophagus. They can be caused by various factors, including certain medications, infections, and even stress.
  • Benefits of Omeprazole: By decreasing the stomach acid’s production, Omeprazole creates a less acidic environment in the stomach. This aids in the healing of active ulcers and reduces the chances of new ulcers forming.
  • Protection: Especially in dogs that need to be on certain medications known to cause ulcers, Omeprazole can act as a preventive measure.

Manage Acid Reflux:

  • What is Acid Reflux?: Acid reflux, or gastroesophageal reflux disease (GERD), occurs when stomach acid frequently flows back into the tube connecting the mouth and stomach (esophagus). This backwash (acid reflux) can irritate the lining of the esophagus.
  • Symptoms: Dogs with acid reflux might experience vomiting, pain while swallowing, loss of appetite, weight loss, and coughing.
  • Role of Omeprazole: The drug minimizes the acidity in the stomach, reducing the damage and irritation caused by acid flowing back into the esophagus.

Provide Relief from Symptoms of Esophagitis:

  • Understanding Esophagitis: Esophagitis is the inflammation or irritation of the esophagus. It can be caused by acid reflux, infections, certain medications, or foreign bodies (like if a dog swallows a bone). Chronic cases might lead to difficulties in swallowing or even obstruction.
  • How Omeprazole Helps: By reducing the amount of acid in the stomach, Omeprazole helps ensure that if there is any reflux, it is less acidic and thus less damaging. This can significantly aid in the healing process of the inflamed esophagus and provide relief from associated symptoms.

When considering Omeprazole or any medication for your pet, it’s always crucial to consult with a veterinarian. They can provide guidance on the correct dosage, potential side effects, and monitor the dog’s response to the treatment.

Dosage and Administration:

It’s essential to follow your veterinarian’s guidance on the correct dosage and duration of treatment for your dog. Typically, Omeprazole is given once daily before feeding. Ensure that the dog consumes the whole pill.

Potential Side Effects:

Just as with any medication, there might be side effects. Some dogs might experience:

  • Vomiting
  • Diarrhea
  • Flatulence
  • Changes in appetite or behavior

If you notice any adverse reactions, it’s crucial to consult your veterinarian immediately.

Important Considerations:

  • Omeprazole is not FDA-approved for veterinary use, but it is commonly prescribed as an extra-label drug.
  • Always ensure you’re using the right dosage and not a human-prescribed dose for your dog.
  • Pregnant or nursing dogs should only be given Omeprazole if the potential benefits outweigh the risks.


While Omeprazole might be more commonly recognized as a human medication, it plays a significant role in treating specific gastric conditions in dogs. As always, consult your veterinarian before administering any medication to ensure the safety and health of your beloved pet.

Doctor Xeeshan

Doctor Xeeshan

I am Doctor Xeeshan, located in Lahore, Punjab, Pakistan. In this blog, I am providing authentic information about dog breeds, diseases, medications, etc.


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