Zeniquin is the trademark of Zoetis Pharmaceuticals. It contains marbofloxacin, a third-generation antibiotic drug, belongs to the fluoroquinolone class of antibiotics. In the following article, I would explain How Zeniquin used to treat ear infection in dogs? as well as will provide brief information about Zeniquin dosage for dogs, interactions with other medicines, indications, contra-indications, side effects, and storage, etc.

What exactly is Zeniquin?

Zeniquin (marbofloxacin) is a type of antibiotic used to treat bacterial infections in animals. It is used to treat infections of the skin, respiratory tract, urinary tract, and other body systems in dogs, cats, and other animals.

Zeniquin is available in the form of tablets or a liquid suspension and is usually given orally. It is generally well tolerated by animals, but like all medications, it can have side effects, including diarrhea, vomiting, and loss of appetite. It is important to use Zeniquin only under the guidance of a veterinarian, as improper use of antibiotics can contribute to the development of antibiotic-resistant bacteria.

Why using Zeniquin For Ear Infection in Dogs?

Ear infections are common in dogs and can be caused by a variety of factors, including bacteria, yeast, allergies, and more. These infections can cause a range of symptoms, including pain, discomfort, discharge, and difficulty hearing. If left untreated, ear infections can lead to serious complications, including damage to the ear canal and hearing loss.

One option for treating ear infections in dogs is the use of antibiotics, and Zeniquin (marbofloxacin) is a popular choice. Here are a few reasons why Zeniquin may be an effective treatment option for dogs with ear infections:

  1. Zeniquin is a broad-spectrum antibiotic: This means that it is effective against a wide range of bacteria, including the types of bacteria that are commonly responsible for ear infections in dogs.
  2. Zeniquin has good penetration into the ear: The medication is able to reach deep into the ear canal and effectively kill the bacteria causing the infection.
  3. Zeniquin has a high success rate: Studies have shown that Zeniquin is effective in treating ear infections in dogs and has a high success rate.
  4. Zeniquin is easy to administer: Zeniquin is available in tablet or liquid form and can be easily administered orally.

While Zeniquin can be an effective treatment option for dogs with ear infections, it is important to use it only under the guidance of a veterinarian. Overuse or improper use of antibiotics can contribute to the development of antibiotic-resistant bacteria, which can make it more difficult to treat future infections.

Veterinarian Examining Dog's Ear

Why some Dogs are more prone to Ear Infections?

Mammalians, especially dogs and cats are more prone to build ear infection. Because their ear canal is more vertical than humans. Their ear canal may hold fluids, like water after bathing, moisture, or wax, etc. 

The accumulation of dirty wax in the dog’s ear canal may lead to developing an ear infection. There are three types of infections caused by bacteria in dogs. 

  1. External Ear Infection
  2. Median Ear Infection
  3. Internal Ear Infection
An external ear infection is more common than other ones and is less chronic. It may be treated easily and less fatal to your dog’s health. But if a dog develops a median or internal infection than you must take it more seriously because it belongs to the ear canal.
Zeniquin (marbofloxacin) is an FDA (Food and Drug Administration) approved drug for dogs and other animals. It is the best antibiotic to treat soft-tissue infections in pets. A third-generation, broad-spectrum antibiotic drug that has sufficient ability to fight against Gram-Positive and Gram-negative types bacteria. 
It belongs to the fluoroquinolone class of antibiotic drugs, ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin are some of their best antibiotics compositions available for humans.


Zeniquin (Marbofloxacin) is a broad-spectrum antibiotic which is very effective against large types of bacteria that cause skin infections in dogs, urinary tract infection, ear infection, nose infection, eye infection in dogs, respiratory tract infection, wounds, and other soft tissue infections, etc.

Zeniquin Dosage For Dogs Ear Infection

It is available in 25mg, 50mg, 100mg, and 200mg tablets form. This is a prescription drug and only available on a registered Veterinarian prescription only. The unnecessary use of antibiotic drugs may cause antibiotic-resistant in the body that may reduce antibiotic efficacy and consequences.
A veterinarian doctor may suggest a complete dosage plan for your dog after diagnosing the severity of ear infection. An ear infection treatment of dogs with Zeniquin (marbofloxacin) may take 7-14 days depending on the condition. 
1.25mg per lb and 2.5mg per kg is the recommended dose for dogs. But as said before a Veterinarian may suggest the best-recommended dose for your pet.
Side Effects of Zeniquin for Dogs
This drug may not be suitable for some pets. It may cause some common side effects or adverse reactions within a few hours. These are the side effects your dog may suffer after using it,
  • Diarrhea
  • Vomiting
  • Nausea
  • Redness on skin
  • Rashes on skin
  • Change in behavior 
Every living organism is different from each other. Therefore, a few may get adverse reactions by using this drug.


This drug is contraindicated for all animals who are hypersensitive to the Fluoroquinolone family of antibiotics. Marbofloxacin belongs to fluoroquinolone (norfloxacin, moxifloxacin, gemifloxacin, levofloxacin, etc) class of drugs. So, if your pet is hypersensitive to any of fluoroquinolone then consult your Vet before using it. 


Zeniquin is a good choice for treating ear infections in dogs due to its broad-spectrum activity, ability to penetrate the ear, high success rate, and ease of administration. However, it is important to use it only as directed by a veterinarian to help prevent the development of antibiotic resistance.

Doctor Xeeshan

Doctor Xeeshan

I am Doctor Xeeshan, located in Lahore, Punjab, Pakistan. In this blog, I am providing authentic information about dog breeds, diseases, medications, etc.


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